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Biomedizinische Forschung
ServicesBiomedical ResearchResearch Infrastructure OUOrganizational unitsMedical University of Graz

Diagnostic Laboratory

Blood tests are essential in human and veterinary medicine for precise health diagnostics. A wide range of biomarkers allows early identification of specific disease patterns. In preclinical research, blood analysis has also become an indispensable translational tool. The expertise of the diagnostic laboratory is available to researchers at the Medical University of Graz as well as to external cooperation partners.

The biomedical research facility is equipped with three automated veterinary diagnostic analysis systems. These enable comprehensive blood counts, including histograms, to be generated within minutes from minimal volumes of whole blood. For clinical-chemical analyses, 21 parameters are available to create ion, metabolite, or enzyme profiles precisely tailored to the research question.

Comprehensive blood count

From at least 20 µL of fresh EDTA whole blood using Smart-V5 for 5-part or V-SIGHT for 3-fold leukocyte differentiation. The following parameters are measured:

  • Erythrocytes (total count (RBC), hemoglobin (Hb), mean cell volume (MCV), hemoglobin per cell (MCH), hemoglobin concentration (MCHC), distribution width (RDW), hematocrit (HCT))
  • Leukocytes (total count (WBC), lymphocytes, monocytes, granulocytes (neutrophils, eosinophils, and basophils—depending on differentiation))
  • Thrombocytes (total count (PLT), mean platelet volume (MPV), distribution width (PDW), plateletcrit (PCT))

Clinical-chemical analyses

From 20–200 µL EDTA or heparin plasma or serum using Dri-Chem NX500i (Fujifilm). The following parameters are measured:

  • • Metabolites (glucose (GLU), urea / BUN (UREA), creatinine (CRE), uric acid (UA), total bilirubin (TBIL), ammonia (NH3), total cholesterol (TCHO), triglycerides (TG), calcium (Ca), phosphorus (PHOS / IP), magnesium (Mg))
  • • Enzymes (alanine aminotransferase (ALT / GPT), aspartate aminotransferase (AST / GOT), alkaline phosphatase (ALP), gamma-glutamyltransferase (GGT), lactate dehydrogenase (LDH), creatine kinase (CK / CPK), amylase (AMYL), lipase (LIP))
  • • Proteins (total protein (TP), albumin (ALB))
  • • Electrolytes (sodium (Na⁺), potassium (K⁺), chloride (Cl⁻))
  • • Canine CRP (cCRP)

Registration

Please register your blood analyses in advance: a lead time of at least 3 working days is required for blood counts, and at least 14 working days for clinical-chemical analyses. Upon request, the Animal Facility team will gladly assist you with blood sampling.

Diagnostisches Labor

 
E: animal-diagnostic(at)medunigraz.at